The Orioles let Jeremy Guthrie face one batter in the third, and he retired Victor Martinez on a fly ball to center.
Guthrie is charged with one run and three hits in 2 1/3 innings, with two walks and two strikeouts. He threw 51 pitches, 29 for strikes.
Left-hander Chris George has replaced Guthrie.
The Orioles wanted Guthrie to get up one more time, which explains why he came out for the third.