A manager uses six relievers to secure a win, he’s going to wish for a lengthy outing from his starting pitcher less than 24 hours later.

Brandon Hyde watched Jordan Lyles strand two Red Sox runners in the first and second innings and leave the bases loaded in the third. Escape acts that should be applauded, but also left him at 55 pitches.

The forecasted rain wasn’t helping, either – 100 percent chance over the next two hours, the gray sky not offering a counterpoint.

A lineout to begin the fourth was followed by a single, walk and 6-3 double play. Fourteen more pitches, but still no runs.

The slithering out of jams ended in the fifth, with Boston scoring on Franchy Cordero’s sacrifice fly after Xander Bogaerts led off with a double.

OAKLAND – For the Orioles, the opening game of this long road trip in Oakland had a familiar look.

For five innings it was close and low-scoring. The Baltimore offense was scuffling for runs again but the Baltimore pitching was getting the job done. Yet again they were.

On a night when the Orioles reduced their team ERA from an impressive 3.04 to an even better 2.86, they still lost. Four unearned runs in the last of the sixth doomed them to a 5-1 defeat at Oakland.

But right-hander Spenser Watkins was the latest O’s starter to throw well. He allowed two hits and one run over five innings on 67 pitches. He made a bid to stay in the rotation.

“That is always up to Skip on those (rotation) decisions,” Watkins said in the Orioles clubhouse. “But, I’m ready to take the ball whenever they give it to me and I’m going to compete.”

Anthony Bemboom starts behind the plate tonight as the Orioles begin a four-game series in Oakland.

Anthony Santander is in left field, Austin Hays is in right and Ryan Mountcastle is the first baseman. Trey Mancini is serving as the designated hitter.

Mountcastle and Santander have reached base in all nine games.

The infield also includes Ramón Urías at third base. Rougned Odor is at second after yesterday’s pinch-hit two-run single in the eighth inning that broke a scoreless tie against the Yankees.

Spenser Watkins gets his second start after allowing one earned run, but four total, in three innings against the Brewers. He’s never faced the Athletics.

OAKLAND – The Orioles will play in Oakland tonight to start a 10-game road trip that will take them to both coasts and produce series against the Athletics, Angels and Yankees. It will be challenging, but at least they start it on a high note after Sunday’s 5-0 shutout win over the Yankees in Baltimore.

If you were among the large number of fans wondering how much longer they could go without getting clutch hits, the answer was seven more innings as Sunday’s game began. But after going 3-for-30 in the three games before yesterday with runners in scoring position and 7-for-77 for the year through eight games, they finally came through.

And it was the oft-criticized Rougned Odor whose two-run single opened the floodgates, so to speak, and the Orioles got three straight hits with RISP after being 7-for-83 for the year as Odor stood in to pinch-hit in the eighth of a 0-0 tie.

The Orioles beat the Yankees in the series, also winning in 11 innings Friday night. Who knows what might have happened this weekend at the Yard without the hail on Saturday night, which altered the O’s pitching plans.

Speaking of pitching, since Friday, when we pretty much found out lefty John Means would be out for a significant period of time, O’s starters have allowed one earned run. So far – yes, in the smallest of samples – they stepped up.